Which of the following is a characteristic of malignant melanoma?

Malignant melanoma is indeed characterized by changes in existing moles or the development of new pigmented lesions that often resemble moles. The critical aspect that distinguishes malignant melanoma is the alteration in the coloration, border, or size of the mole, which may signify its progression from a benign state to a malignant one. Patients and practitioners should be vigilant for any asymmetry, irregular borders, multiple colors, or changes over time in moles, as these are red flags for melanoma.

This characteristic is a pivotal component of skin cancer awareness and is encapsulated in the ABCDE rule (Asymmetry, Border irregularity, Color variation, Diameter larger than 6mm, and Evolving shape or size), which helps in early detection. The changes in appearance are due to the uncontrolled proliferation of pigment-producing cells (melanocytes), which can lead to more serious health risks if left unchecked.

Understanding that malignant melanoma can significantly change the appearance of a mole allows for better monitoring and eventual early intervention, which is crucial for effective treatment and favorable outcomes.