What syndrome is characterized by excessive cortisone levels and symptoms like moon face and hump back?

Cushing's syndrome is characterized by excessive levels of cortisone, often due to overproduction of cortisol from the adrenal glands or prolonged use of corticosteroid medication. This condition leads to a specific set of symptoms, prominently including "moon facies," which refers to the rounded appearance of the face due to fat redistribution, and "hump back," or a buffalo hump, which is the accumulation of fat on the upper back. These symptoms occur as the body reacts to the excess of cortisone, affecting metabolism and fat distribution.

In contrast, Addison's disease involves insufficient production of cortisol and often presents with weight loss, low blood pressure, and hyperpigmentation. Hyperthyroidism and hypothyroidism are conditions related to an imbalance in thyroid hormones with symptoms that differ significantly from those seen in Cushing's syndrome. Hyperthyroidism may cause weight loss, increased heart rate, and anxiety, while hypothyroidism can lead to weight gain, fatigue, and depression. Understanding these distinctions helps clarify why Cushing's syndrome is the correct answer regarding the symptoms described.